2/26/2024 0 Comments Rose quartz heart shaped necklaceWe fulfill orders within 1-2 business days, and items are typically delivered within 3-6 business days within the US. We ship from Reno, Nevada, and we use USPS First Class Mail. – Avoid contact with perfumes, body oils, and other chemicals. – Remove the jewelry when going to sleep, working out, and showing or swimming. To maintain the quality of your new Healing Designed jewelry, please ensure the following: We hope that you enjoy our timeless pieces as much as we do. Our jewelry pieces are handmade with love and care and we put positive energy and vibes into everything we do and sell.Įach piece is meant to elevate, enlighten, and align the mind + body + spirit. Description The most used stone for love and relationships Opens up heart to unconditional love Encourages forgiveness Heals pain due to breakups, hate. We select only the highest quality home decor, accessories, and healing stones and crystals from trusted sources.
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Meanwhile, measures to accelerate new-drug reviews, including raising the number of staff at the Center for Drug Evaluation (CDE) from 150 in 2015 to 700-plus in 2018 (supplemented by over 600 external committee members), helped clear a backlog of 20,000 applications in two years, according to CDE data. These steps enabled China’s drug discovery and development ecosystem to integrate globally. ![]() The speed and scale of the reform is quite unprecedented in China’s history a 2015 overhaul, with the goal to bring China’s pharmaceutical regulations into line with international standards, had facilitated accession to the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use by 2017. The regulatory environment subdimension showed the largest improvement, with the score advancing from 4.0 in 2016 to 6.2 in 2020. Rapid regulatory reform has supported faster development and approvals Drilling down into each dimension reveals six key takeaways. Our research shows that industry sentiment is steadily improving, with the average rating across all criteria increasing from 4.5 to 5.5 between 20. We polled 129 industry experts for the 2020 edition of the CDII, two-thirds of whom are CEOs or senior executives, to establish the dimensions in which China has made the most progress and the areas that still require attention. Participants rate China on a scale from 0 to 10, with 10 being the highest, and the United States serving as a benchmark with a score of 8 (Exhibit 2). First launched in 2016, the survey asks industry experts to gauge five dimensions that support healthy biopharma innovation: policy environment (split between regulatory reforms and market access policies), funding, research and development (R&D) capability, local innovation output, and integration with global markets. To understand how China’s biopharma innovation ecosystem is evolving and obtain a more nuanced understanding of the drivers behind its growth, McKinsey maintains the China Drug Innovation Index (CDII). Regulatory reforms, the emergence of bioclusters in areas such as the city of Suzhou, talent returning from overseas, and the opening of China’s capital markets have all played a part in enabling Chinese biopharma to emerge on the global innovation stage. China’s innovation ecosystem: A fast and slow evolution ![]() 1 Building China’s pharmaceutical innovation ecosystem–part one of the series research reports: 2015-2020 development review and future prospects, jointly released by China Pharmaceutical Innovation and Research Development Association and the R&D-based Pharmaceutical Association Committee, April 2021, includes all pipelines in preclinical, clinical, and preregistration stages multinationals’ pipeline is accounted for based on the location of the company headquarters. Indeed, Chinese biotechs are leading on IPO fundraising-seven out of the world’s top ten largest biopharma IPOs from 2018 to 2020 originated from China.Ī rapid proliferation of new drug discoveries with the potential to address unmet needs in the domestic market and beyond has helped China increase its share of the global innovation pipeline to 13.9 percent in 2020 from 4.1 percent in 2015. Public debuts for Chinese players have also accelerated, with 23 IPOs in 2020 alone. Biotechnology companies originating in China accounted for $180 billion of that total (Exhibit 1). The market value of publicly listed biopharma innovation players from China across the Nasdaq, Hong Kong Stock Exchange (HKEX), and Shanghai Stock Exchange Science and Technology Innovation Board (STAR) has surged from $3 billion in 2016 to more than $380 billion in July 2021. Innovation in Chinese biopharma is fast becoming a notable story, underscored by significant value creation on global capital markets. In this article, we take the pulse of China’s vibrant innovation ecosystem, look at the key trends driving the biopharma industry, and share thoughts on how multinational pharmaceutical players can tap into innovation opportunities in the world’s second-largest healthcare market. China’s biopharmaceutical ecosystem is experiencing a momentous shift from a formerly generics-focused play into one that nurtures innovation, with profound implications for patients and industry peers. 2/26/2024 0 Comments Dodge rambox bed dimensions![]() Coil-spring rear suspension on Ram 1500 for best-in-class ride and handling.Ram trucks now boast these segment exclusives: Ram Truck has emerged as a full-size truck leader by investing substantially in new products, infusing them with great looks, refined interiors, durable engines and features that further enhance their capabilities. The Ram Truck brand has the most innovative lineup of full-size trucks on the market. Ram 1500 also was named the Truck of Texas by the Texas Auto Writers Association in 2011. Ram 1500's smooth-riding suspension and 20 mpg, 390 horsepower HEMI® V-8 are just two of the reasons it beat the competition. The 20 was named a Consumers Digest Best Buy and AUTOMOBILE Magazine All-Star. Whether focusing on a family that uses its half-ton truck day in and day out, a hard-working Ram Heavy Duty owner or a business that depends on its commercial vehicles every day, Ram has the truck market covered. Creating a distinct brand for Ram trucks has allowed the brand to concentrate on how core customers use their trucks and what new features they'd like to see. The Ram Truck brand continues to establish its own identity and clearly define its customer since its launch as a standalone vehicle brand. And a cargo rail system with sliding, adjustable cleats for infinitely adjustable tie-down versatility.It can be conveniently stowed in the front of the bed when not in use The bed divider creates individual compartments in the pickup bed to separate payload equipment such as tools or equipment. An adjustable bed divider/extender that fits on the lowered tailgate and adds 2 feet of additional length to secure longer loads.Lids include swing hinges with intermediate and full-open positions that lift the lid 90 degrees perpendicular to each side. RamBox bins fit the length of the pickup bed and incorporate the space over each wheel well to secure cargo within a lit, lockable and drainable container. ![]() RamBox side bins create storage along each side of the pickup bed space previously left untouched due to wheel-well intrusion. ![]() The side bins are large enough to hold items including: a set of golf clubs, helmets, toolboxes, kayak paddles, fishing rods, chainsaws or beverage cans and ice.
![]() East is to the right, south is at the bottom, and west is to the left. Study with Quizlet and memorize flashcards containing terms like Which of the following describes the principle of original horizontality, If a sequence of sedimentary units is cut by a fault, what does the principle of cross-cutting relationships tell a geologist, A sandstone contains inclusions of metamorphic rock. The “N” arrow indicates the North direction on this diagram. Once the irregularities are covered, however, the top of the sediment layer will be basically horizontal (e.g., beds C and D, Fig. It shows what the surface of the Earth above these rocks looks like, as though we were looking down from space. You can rotate this view in the 3D model to better see the arrow.įigure 1B is the map view of the block diagram from Figure 1A. ![]() Define the Law of Original Horizontality. It was first proposed by the Danish geological pioneer Nicholas Steno (16381686). The principle is important to the analysis of folded and tilted strata. The “N” arrow indicates the North direction on this diagram. E.8.7.2 Study rock cycle foldable and complete the following diagram and table. The principle of original horizontality states that layers of sediment are originally deposited horizontally under the action of gravity. We do not specify which types of rocks form the layers in these cartoon diagrams. In a real cross section or geologic map, each layer is color coded to be a specific type of rock. The different colors represent layers or beds of different types of rock. The Safari browser is NOT compatible with the 3D models.įigure 1A is a block diagram of horizontal layers or strata. ![]() To view block diagrams, you will need to use a compatible brower. The Principle of Original Horizontality states: Layers of rocks deposited from above, such as sediments and lava flows, are originally laid down horizontally. The Principle of Superposition states : In an otherwise undisturbed sequence of sedimentary strata, or rock layers, the layers on the bottom are the oldest and layers above them are younger. The principle of Original Horizontality: Sedimentary rock layers. In its plainest form, it states that in undeformed stratigraphic sequences, the oldest strata will lie at the bottom of the sequence, while newer material stacks upon the surface to. Stratigraphy is the study of layered sedimentary rocks. The law of superposition is an axiom that forms one of the bases of the sciences of geology, archaeology, and other fields pertaining to geological stratigraphy. After all, some sediment is not originally deposited in flat beds, as you will know from the articles on sedimentology: for example aeolian sand is laid down in cross-beds, and the angle of repose of a sand dune can be as. In order to understand the structural diagrams we will use in this module, it is necessary to remember two principles of stratigraphy. The principle of original horizontality states that sediment is originally laid down flat. Which rock type is the youngest in the exposed sequence SE of the fault a. 26 Original Horizontality and Superposition principle of stratigraphic superposition d. 2/26/2024 0 Comments Rat rod patina paint job![]() started a trend of younger guys that were in to Rockabilly music, dressed in a 1950s Greaser style, and built period correct pre war hot rods, reminiscent of the 1940s, 50's, and early 60s. Anthony stated that to him and his car club, their traditional hot rods were lacking certain elements like paint and/or upholstery, and were similar to rat bikes of their time period, thus the name Rat Rods. In the early 1990s, Anthony Casteneda thought of the word when they were interviewed in a Rod & Custom magazine article. The origin of the term "rat rod" is the subject of dispute, but was definitely coined by one specific person in the Shifters So. Due to the beater's cheap upholstery, primer covering (instead of paint), and lack of chrome or polished metals, it has been considered a progenitor of the rat rod. The December 1972 issue of Rod & Custom Magazine was dedicated to the "beater", a low-budget alternative to the early car models that were slick and customized. ![]() Origins 1932 Ford coupe rat rod in Sheffield, Vermont. Few cars in the '50s looked like this, but today they can, in countless creative and fun ways. The customs can have slit windows and scrape the ground. with giant rear tires, lots of carburetors, open pipes, and tall gearshifts. They're artistic, fun, and sensational reinterpretations of late-'40s/early-'50s hot rodding as a culture that includes music, clothing, hairstyles, and tattoos. Second are what I personally call Rat Rods, as a positive term. Those are cars built the way rods were built in the '30s, '40s, and early '50s, with a primary emphasis on low-buck and home-built, using period-correct components ranging from flathead to nailhead engines, wide whitewall tires to skinny blackwall bias-plies, and black primer to hand-rubbed paint. I see what are referred to as Rat Rods today comprising three elements: First are the traditional rods and customs. Rodding scribe Pat Ganahl took a broad look at the rat rod trend and had this to say: Recently, using the term "rat rod" has been derided as being incorrect when describing any vehicle that appears unfinished or is built simply to be driven. The owner of the vehicle was typically responsible for most, or all, of the work present in the vehicle. Later-era post-war vehicles were rarely constructed without fenders and were often customized in the fashion of kustoms, leadsleds, and lowriders Maltese crosses, skulls, and other accessories were often added. The bodies are frequently channeled over the frame and sectioned, or the roofs are chopped, for a lower profile. Many early (pre- World War II) vehicles were not built with fenders, hoods, running boards, and bumpers. The typical rat rod is a late-1920s through to late-1950s coupe or roadster, but sometimes a truck or sedan. Biker, greaser, rockabilly, psychobilly, and punk sub-cultures are often cited as influences that shaped rat rodding. Rat rods are meant to loosely imitate, in both form and function, the "traditional" hot rods of the era. The rat rod's inception signified a throwback to the hot rods of the earlier days of hot-rod culture-built according to the owner's abilities and with the intention of being driven. Originally, rat rods were a counter-reaction to the high-priced "customs" and typical hot rods, many of which were seldom driven and served only a decorative purpose. The term has also been applied to a style of hot rod or custom car that broadly imitates or exaggerates the early hot rods of the mid-twentieth century, unlike the "traditional" hot rod, which is one built at that time or a close re-creation of one of such. Whether or not so appointed, the rat rod uniquely conveys its builder’s imagination. These parts can include non-automotive items that have been repurposed, such as a rifle used as a gear shifter, wrenches as door handles, or hand saws as sun visors. Style of vehicle customization An example of a rat rod Ford rat rodĪ rat rod, as usually known today, is a custom car with a deliberately worn-down, unfinished appearance, typically lacking paint, showing rust, and made from cheap or cast-off parts. ![]() ![]() Peas: Swap the peas with green beans, steamed broccoli, or asparagus for a pop of color, fiber, and a serving of veggies.Tuna: Not a fan of tuna fish? Use just one can of tuna (or replace it entirely) and combine that with canned chicken or cooked chicken breast cut into small pieces.Crunchy topping: Instead of Ritz crackers, try crushed potato chips or crispy fried onions.I don’t recommend using skim or low fat milk if going for a creamy mac and cheese dish, but I certainly won’t stop you! Sprinkle with remaining fried onions bake 5 minutes longer or until heated through. Stir in the tuna, soup, milk, peas, mushrooms and half of the fried onions. Other dairy: You can use half and half to make it extra rich. Prepare macaroni and cheese according to package directions.Bacon: Add some bacon bits or crumbled bacon on top to make it deluxe cheesy tuna mac with a subtle smoky touch. Boil the mac n cheese according to the box (7 to 8 minutes at a rapid, rolling boil).Sour Cream: To make this mac n cheese extra creamy stir in about a half cup of sour cream when you add the cheese.Add the flour and a pinch of salt and stir well, cooking an additional 2-3 minutes on medium-low heat. Add onions and cook on medium heat until soft, about 5 minutes. Fresh herbs: Green onions, chopped fresh basil, or parsley are great to sprinkle over the top. Cook noodles in salted water until al dente, or slightly undercooked by 2 minutes.Spicy Tuna Mac: Stir in a tablespoon of your favorite hot sauce (I love Texas Pete!).Notes: Kraft® Mac and Cheese Tuna Casserole, Kraft® Mac and Cheese Tuna Casserole. Bake in the oven at 350 degrees F for 10 minutes.Sprinkle crushed Ritz crackers over the top.Pour the cheesy noodles into a greased 1 1/2 quart or quart casserole dish.Mix in the milk, cream of mushroom soup, and cheese packets until well mixed.After baking, let the macaroni rest for 5-10 minutes to set up. Sprinkle the fried onions evenly out overtop. Add in the tuna and stir to break up the chunks. Lightly spray a small casserole dish with nonstick spray, and then transfer the macaroni and cheese mixture to it.Cook the butter until melted and the onions are soft.Return the empty pot to the stove over medium heat.Then dump the contents into a colander and rinse under cold water. Just before draining the water, stir in the frozen peas.Cook your macaroni noodles according to package directions until al dente.Notes: Easy Tuna Mac n' Cheese, Super Quick & Easy Tuna Casserole One box of Kraft Macaroni & Cheese (or store brand, whatever your preference), heat 1 cup peas (canned or frozen) in Top with remaining shredded cheese bake 5 min. Spoon 1/3 of the Dinner mixture over tomato sauce in casserole top with layers of half the tuna mixture and 1/2 cup of the remaining shredded cheese. Add egg and 1/2 cup shredded cheese to Dinners mix well.Mix remaining tomato sauce with tuna, peas and red peppers. Meanwhile, blend next 3 ingredients in blender until smooth spoon 1/2 cup into 3-qt.Prepare Dinners in large saucepan as directed on package.Notes: Mac and Cheese Tuna Casserole, Ingredients 1 small Onion (1 cup), finely diced 2 boxes Macaroni and cheese, like Kraft 2 cans (5oz) Tuna in water, drained 1 ½ cups Frozen Bake until onions are brown and cheese is melted, another 5 minutes. Sprinkle with Cheddar cheese, then sprinkle French-fried onions over top. Bake in the preheated oven for 30 minutes.Pour mixture into the prepared baking dish. Combine drained macaronis, peas, and tuna in a bowl.Stir in condensed soup and cook until heated through, about 3 minutes. Add milk and cheese sauce packet mix well. ![]() Melt butter in the same saucepan over medium heat.Drain macaroni, then rinse under cold water and drain again. Lay 1/2 of the butter across the bottom of a 2-quart, microwave-safe casserole. Mix cooked noodles with tuna, sour cream, 1/4 cup milk, onion soup mix, Worcestershire sauce, garlic powder, seasoned salt, salt, and pepper. Stir in macaroni from the box and cook for 7 minutes. Cook egg noodles at a boil until tender yet firm to the bite, 7 to 9 minutes. Bring 6 cups water to a boil in a medium saucepan.Spray a 9x13-inch baking dish with nonstick spray. Preheat the oven to 350 degrees F (175 degrees C). 2/26/2024 0 Comments Anytransos x![]() ![]() ![]() Trival Knowledge iBolts Quiz Kit is a collection of more than 100 questions and answers covering different topics in various disciplines and occupations. The tool is not able to generate statistics with the right and incorrect answers, and does not let you finish the test in a limited amount of time and configure audio notifications. However, professionals may be disappointed by the application’s poor support for configuration settings. 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If you are a resident of the European Union, you have the right to cancel the contract for a purchase of Digital Content from Kobo for a refund within a period of 14 days beginning with the day after purchase. CANCELLATION POLICYĮxcept as set out in this agreement, all sales are final. By downloading or otherwise accessing Digital Content from the Kobo Service, you hereby acknowledge and agree to these terms. You may not modify, transmit, publish, participate in the transfer or sale of, reproduce, create derivative works from, distribute, perform, display, or in any way exploit, any of the content of any Digital Content, in whole or in part. Any other use of Digital Content downloaded or accessed from the Kobo Service is strictly prohibited. The download of, and access to Digital Content is available only to Customers and is intended only for your personal and non-commercial use. All Digital Content on the Kobo Service is the exclusive property of the publisher or its licensors and is protected by copyright and other intellectual property laws. The Kobo Service sells licenses to literary works (“Digital Content”) to end user customers that have created a Kobo account (“you” or “Customer”) only. SALES TO CUSTOMERS ONLY RESTRICTIONS ON USE 100, Toronto, Ontario, Canada M6K 1A7) in countries outside of Europe (in each case, as applicable), that, amongst other free services made available as part of the Kobo Service provides Customers with access to purchase Digital Content. Dublin, Ireland) in Europe, and by Rakuten Kobo Inc. ![]() Kobo is an online service (“Kobo Service”) provided through Kobo Software Ireland Limited (Block 3, Blackrock Business Park, Carysfort Ave, Blackrock Co. 2/25/2024 0 Comments Gb whatsapp app
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